Olfactory Neuroblastoma Treated by Endoscopic Surgery Followed by Combined External Beam Radiation and Gamma Knife for Optic Nerve and Chiasm Sparing: A Case Report
نویسندگان
چکیده
We describe the multimodality treatment regimen of a 53-year-old man diagnosed with olfactory neuroblastoma (Kadish stage C) in the right nasal cavity extending into the ethmoid sinus and across the cribriform plate. Endoscopic surgery for tumor resection was followed by a combination of external beam radiotherapy and stereotactic radiosurgery boost with concurrent chemotherapy. The novel combination of dual radiation therapies allowed for the preservation of the nearby optic structures while providing an adequate dosage to a sufficient volume of the afflicted tissue.
منابع مشابه
Case report: recurrent olfactory neuroblastoma nasal cavity in young boy refractory to chemotherapy with remission after radiotherapy and sparing of left eye.
Olfactory neuroblastomas make up about 3-5% of malignant intra-nasal tumors and originate from the olfactory neuroepithelium lining the roof of the nasal vault. There exist no optimum treatment guidelines from randomized data due to paucity of patients. Treatment options range from minimal surgery to extensive cranio-facial resections and adjuvant radiotherapy. In this case a tumor engulfing op...
متن کاملGamma Knife® radiosurgery for recurrent intracranial olfactory neuroblastoma (esthesioneuroblastoma): a case report
BACKGROUND We report the use of salvage radiosurgery to manage an aggressive olfactory neuroblastoma (esthesioneuroblastoma) with multiple recurrences and intracranial extension. CASE PRESENTATION A 43-year-old Caucasian woman presented 11 years ago with progressive nasal blockage and headaches. A necrotic polyp originating in her left middle meatus and extending to the ethmoid air cells and ...
متن کاملLinear Accelerator Based Stereotactic Ablative Radiation of Orbital Malignancies
Orbit has a complex anatomy with multiple structures embedded in it. Primary malignant tumors of the orbit are rare. Orbital neoplasms are usually multifaceted and require an interdisciplinary approach. They occur in adults over the age of 60 years. But benign orbital conditions can occur at young age [1]. After confirming the diagnosis of orbital tumors; various treatment methods performed are...
متن کاملGamma knife radiosurgery for pituitary tumours.
Stereotactic radiosurgery with the gamma knife delivers focused radiation from a cobalt-60 source in a single session to a pituitary tumour with minimal radiation to the adjacent normal brain tissue. Currently, gamma knife radiosurgery is predominantly used to treat failed pituitary surgery, although it has a role as a primary treatment for patients unwilling or unsuitable, for medical reasons,...
متن کاملComparison of Volumetric Modulated Arc Therapy and Three-Dimensional Conformal Radiotherapy in Postoperative High-Grade Glioma: A Dosimetric Comparison
Introduction: We aimed to dosimetrically compare three-dimensional conformal radiotherapy (3D-CRT) and volumetric modulated arc therapy (VMAT) in terms of planning target volume (PTV) coverage, organ at risk (OAR) sparing, and conformity index (CI). Material and Methods: Planning data of 26 high grade glioma (HGG) patients were used. Prescrib...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
دوره 2011 شماره
صفحات -
تاریخ انتشار 2011